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KMID : 0616119820130010026
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Korean Journal of Pharmacognosy
1982 Volume.13 No. 1 p.26 ~ p.32
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Studies on the Efficacy of Combined Preparations of Crude Drugs (Ⅴ) Effect of “ Whangryonhaedok - Tang ”on the Anti - inflammatory , Ileum of Mice , Blood Pressure , Blood Glucose , Total Cholesterol and Antibacterial Activity
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홍남두/Hong ND
김종우/두호경/김남재/Kim JW/Doo HK/Kim NJ
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Abstract
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In order to investigate the effect of "Whangryonhaedok-Tang" on the anti-inflammatory, ileum of mice, blood pressure, blood glucose, total cholesterol and antibacterial activity, those pharmacological actions were conducted. The results of this studies were summerized as follows; Rat hind paw edema induced by acetic acid was inhibited. In mice, tone of intestinal smooth muscle was suppressed with the treatment of sample and intestinal contractions induced by BaCl₂ was inhibited. Hypertensive effect was not observed in rabbits but was observed by the water extract of "Whangryonhaedok-Tang" excluded Phellodendri Cortex in rabbits. The incleased blood glucose levels in alloxandiabetic rabbits were significantly decreased by the oral administration of the sample I after 6 days. The total cholesterol levels in alloxan-induced rabbits were significantly decreased by the oral administration of the sample I after 9 days. Antibacterial activity was observed. In addition, we thought the pharmacological actions were significantly noted by the sample III(Methanol soluble fraction) because of the purification of effective components.
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